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CERAMENT™BONE VOID FILLER

Bone Support AB · Model A0210-08 · UDI-DI 07350055430035

MQV Prescription
10
510(k) clearances
2,073
Adverse events (45 deaths)
120
Recalls
225
Facilities

Description

CERAMENT BONE VOID FILLER is a fast-setting, injectable and moldable ceramic bone graft substitute intended for filling bone voids/gaps. The material consists of a powder and a liquid component. The major constituents of the powder are hydroxyapatite and calcium sulfate hemihydrate. The liquid component (C-TRU) contains Iohexol as a radio-contrast enhancer. Mixing the components with the combined mixing injection (CMI) device, results in a viscous material intended to set ex vivo or in vivo. By combining hydroxyapatite and calcium sulfate a balance is achieved between implant resorption rate and bone in-growth rate. Calcium sulfate acts as a resorbable carrier for hydroxyapatite. Hydroxyapatite has a slow resorption rate, high osteoconductivity, promoting bone in-growth and gives long term structural support to newly formed bone. The ceramic bone graft substitute is placed into the bone defect under visual inspection or under radiographic monitoring during open or percutaneous surgery. The paste may be injected into the defect, molded by hand and digitally placed into the defect, or used to prepare beads that are placed into the defect. The accompanying injection device (ID) and Tip Extenders may be used to facilitate the filling of the bone defect. When fully set in vivo, CERAMENT BONE VOID FILLER is drillable and can be used to augment hardware during the surgical procedure.

Recalls

DateFirmReason
2026-07-02IsoTis OrthoBiologics, Inc.Demineralized bone matrix (DBM) in resorbable mesh indicated for use with autograft as a bone graft extender in the posterolateral spine and pelvis, were filled with approx. 4.5 cc
2026-03-25Orthorebirth Co LtdResorbable bone void filler falls outside standard specifications.
2026-03-25Orthorebirth Co LtdResorbable bone void filler falls outside standard specifications.
2026-03-09XTANT Medical Holdings, IncProducts were incorrectly labeled with a 5-year shelf life. The approved and validated shelf life is four years.
2025-09-02Berkeley Advanced Biomaterials, LLCDue to incorrect product label (Incorrect product name identified on outer packaging).
2025-04-07SCIENCE & BIO MATERIALSVials of implant bone granules may contain less product then specified on labeling.
2024-11-27IsoTis OrthoBiologics, Inc.Hydration issue resulting in the product being less cohesive and moldable than intended due to an issue with the polymer.
2024-11-27IsoTis OrthoBiologics, Inc.Incorrect expiration date listed on the outer box, which does not align with the correct expiration date listed on the inner tray.
2023-12-22Musculoskeletal Transplant Foundation, Inc.Filling process qualification did not demonstrate adequate process capability. Possible consequences include extended surgery time due to extrudability issues.
2023-12-22Musculoskeletal Transplant Foundation, Inc.Filling process qualification did not demonstrate adequate process capability. Possible consequences include extended surgery time due to extrudability issues.

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Data compiled from public U.S. FDA sources (GUDID, 510(k)/PMA, MAUDE, recalls, establishment registration). Adverse-event reports are unverified and do not establish causation. Informational only — not medical, clinical, or regulatory advice.